Close Menu

    Subscribe to Updates

    Get the latest creative news from FooBar about art, design and business.

    What's Hot

    SHIFT HR Compliance Training: Pioneering the Future of Workplace Culture and Compliance

    July 10, 2025

    Edensoft: Pioneering AI and Cloud Solutions for A Smarter Future

    July 10, 2025

    The Heart and Strategy Behind Altasciences’ Marketing Evolution

    July 3, 2025
    Facebook X (Twitter) Instagram LinkedIn
    • About Us
    • Press Release
    Saturday, July 12
    Facebook X (Twitter) LinkedIn Instagram
    Business Leaders Review: Best Business Magazine and News OnlineBusiness Leaders Review: Best Business Magazine and News Online
    • Home
    • Magazines
    • Featured Leaders
    • Technology
      • Big Data
      • Artificial Intelligence
      • Robotics
      • Cloud
      • Cyber Security
      • Storage
      • IoT
      • Blockchain
      • Data Analytics
    • Industry
      • Banking & Finance
      • Construction
      • Digital Marketing
      • Economy
      • Education
      • EV Industry
      • Food & Beverage
      • Healthcare
      • Legal
      • Manufacturing
      • Mining & Metals
      • Pharmaceutical
    • Testimonials
    • Latest News
    • Blogs
    • Awards
    • Our Clients
    Business Leaders Review: Best Business Magazine and News OnlineBusiness Leaders Review: Best Business Magazine and News Online
    Home » BioMed X and Merck Expand Collaboration Aiming to Leverage Cancer-Specific Vulnerabilities for Targeted Therapies
    Press Release

    BioMed X and Merck Expand Collaboration Aiming to Leverage Cancer-Specific Vulnerabilities for Targeted Therapies

    By Business Leaders ReviewApril 4, 2023

    After successfully completing a project in RNA splicing in cancer this January, BioMed X and Merck continue their oncology collaboration to explore tumor immunogenicity enhancers.

    Heidelberg, Germany, April 4, 2023. BioMed X, an independent biomedical research institute, announces the start of its new research project – “New Strategies to Enhance the Immunogenicity of Tumors” – in collaboration with Merck. The focus of this new research group will be to develop novel approaches for enhancing tumor immunogenicity to broaden the population of patients who could benefit from cancer immunotherapy.

    “What if we could overcome the immunosuppressive microenvironment of solid tumors with a novel targeted approach?” asks Dr. Christian Tidona, Founder and Managing Director of the BioMed X Institute. “This call for application is inviting original research proposals that explore new ways to enhance the immunogenicity of tumors and thus boost the efficacy of immune checkpoint inhibitors,” explains Dr. Tidona.

    A high mutational burden, as well as aberrant mRNA splicing, are sources of neoantigens: unique antigens presented by tumor cells capable of eliciting an effective anti-tumor immune response. The most recently completed BioMed X project was also a Merck collaboration investigating RNA splicing patterns in cancer. “Using a new bioinformatic approach, we were able to query splicing variants that are unique to certain cancers,” said Dr. Alexandra Duarte, former group leader at the BioMed X Institute. “Such splicing abnormalities can shape the complex pathophysiology of cancer cells, including through the expression of immunogenic neoantigens,” added Dr. Duarte, now a Senior Scientist in the Department of mRNA Cancer Immunotherapies of Prof. Dr. UğurŞahin at HI-TRON in Mainz, Germany.

    The new project launched today, marking the tenth joint research group between the two partners, expands this line of research by targeting tumor-specific DNA Damage Repair (DDR) mechanisms or exploiting tumor-intrinsic DDR defects to increase the tumor mutational burden and immunogenicity. Researchers who are interested in becoming part of this new BioMed X research team in Heidelberg are invited to respond to this international call for application by submitting a project proposal via the BioMed X Career Space at https://career.bio.mx/call/2023-BMX-C01 before May 28, 2023.

    Related Posts

    Breaking Barriers: Shelly Castle’s Story of Empowerment and Success

    May 9, 2025

    Adeption offers 50 scholarships for adaptive leadership program

    May 2, 2025

    KBP to Contest Injunction Obtained by Novo Nordisk

    March 3, 2025

    Fcode Labs to Release Pioneering Whitepaper on the Power of AI in Delivering Exceptional Customer Experiences

    February 14, 2025

    Microsoft Dynamics 365: The Undisputed Leader in Gartner’s Magic Quadrant

    January 20, 2025

    Localis 365: the solution that makes tax management simpler in Latin America

    December 13, 2024
    Top Posts

    Heatwaves Threaten Data Centre Cooling: Aggreko Urges Proactive Planning

    July 3, 2025

    Meta Bets $14 Billion on AI Superintelligence and Global Talent Hunt

    June 27, 2025

    Meta Unveils V-JEPA 2 AI Breakthrough to Help Robots Understand the Physical World

    June 13, 2025
    Don't Miss

    SHIFT HR Compliance Training: Pioneering the Future of Workplace Culture and Compliance

    July 10, 2025

    In the fast-moving world of HR compliance, where evolving regulations and shifting workplace dynamics constantly…

    Edensoft: Pioneering AI and Cloud Solutions for A Smarter Future

    July 10, 2025

    The Heart and Strategy Behind Altasciences’ Marketing Evolution

    July 3, 2025

    Brewing Purpose: How Lori Jones and Black•ology Coffee Are Blending Culture, Confidence, and Community

    July 3, 2025
    Stay In Touch
    • Facebook
    • Twitter
    • Instagram
    • LinkedIn
    About Us
    About Us

    Business Leaders Review is a global print and digital monthly and yearly magazine, which provides a platform to showcase business/tech leaders and their company’s profile from various sectors. Our aim is to publish the c-suite leaders stories.

    We are helping the leaders & readers to showcase their ideas and innovations to the business and tech world in this current market situation along with their awards and achievements. Doing so we hope to leverage thousands of businesses and personnel around the globe.

    Most Popular

    Heatwaves Threaten Data Centre Cooling: Aggreko Urges Proactive Planning

    Meta Bets $14 Billion on AI Superintelligence and Global Talent Hunt

    Meta Unveils V-JEPA 2 AI Breakthrough to Help Robots Understand the Physical World

    Latest Magazines
    Facebook X (Twitter) LinkedIn Instagram
    • Home
    • Our Clients
    • TECHNLOGY NEWS
    • Industry News
    • Contact Us
    • Privacy Policy
    • Reprints and Permissions
    © 2025 Business Leaders Review LLC | All Rights Reserved | Empowering Communication Globally

    Type above and press Enter to search. Press Esc to cancel.